MMP17

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MMP17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,753 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MMP17-associated GO terms across cancer lineages are Striated muscle contraction, Actin filament depolymerization, and Cytosolic transport. Each is linked with MMP17 in more than 7 cancer types. Because this analysis shows association rather than direction, both MMP17-to-partner and partner-to-MMP17 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP17→partner) and Y-score (partner→MMP17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEStriated muscle contraction →+0.077+1.266<.001<.00138
SKINActin filament depolymerization →+0.122+1.891<.001<.00137
SKINCytosolic transport →+0.053+2.048<.001<.00137
BLOOD_LymphomaHost-mediated perturbation of viral process →+0.037+0.712.005.00828
BLOOD_LeukemiaSkeletal muscle fiber development →+0.141+1.577<.001.00537
STOMACHAorta smooth muscle tissue morphogenesis →+0.863+1.163.003.00437
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

Exploration