Across TCGA patient cohorts, MME protein abundance is significantly associated with the RNA expression of many other genes, with 12,132 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MME-associated genes across cancer lineages are MME-AS1, RARRES2, and LOX. Each is linked with MME in more than 7 cancer types. Because this analysis shows association rather than direction, both MME-to-partner and partner-to-MME results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MME→partner) and Y-score (partner→MME) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MME-AS1 →	+1.126	+0.515	<.001	<.001	3	8
HNSC	RARRES2 →	+1.298	+0.617	<.001	.004	3	5
BRCA	LOX →	+1.531	+0.674	<.001	<.001	3	5
LSCC	RCN3 →	+0.816	+0.716	<.001	<.001	3	5
GBM	C5AR1 →	+0.992	+0.544	<.001	<.001	3	5
HNSC	LINC01050 →	+0.920	+0.581	.008	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,132 associations by consensus.

Exploration

MME survival (RNA) · tumor vs normal (RNA) · all MME data types