MME

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MME RNA expression is significantly associated with the go_rna of many other GO terms, with 5,923 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MME-associated GO terms across cancer lineages are Lactam metabolic process, Maintenance of protein location, and Positive regulation of extracellular matrix organization. Each is linked with MME in more than 19 cancer types. Because this analysis shows association rather than direction, both MME-to-partner and partner-to-MME results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MME→partner) and Y-score (partner→MME) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaLactam metabolic process →+2.043+4.943<.001<.001320
BONEMaintenance of protein location →+0.142+4.202<.001<.00139
LIVERPositive regulation of extracellular matrix organization →+0.139+3.243.001.00239
URINARY_TRACTResponse to glycine →+1.710+3.803<.001<.00139
BREASTRelaxation of smooth muscle →-0.283-2.854<.001<.00139
BONEMaintenance of protein location in cell →+0.142+4.133<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,923 associations by consensus.

Exploration