MMADHCP2

Across TCGA pan-cancer cohorts, MMADHCP2 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MMADHCP2 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MMADHCP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MMADHCP2 expression acts as an unfavorable survival marker, although some lineages such as DLBC and READ show a favorable association.

COAD, CESC, and PAAD are the cancer types where MMADHCP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	IV	0.283	0.728	<.001	56	view →
CESC	OS	Quartile	II,III,IV	0.325	0.846	.007	44	view →
PAAD	OS	Median	II,III,IV	0.485	0.681	.001	40	view →
BRCA	OS	Quartile	II,III,IV	0.435	0.697	<.001	40	view →
LUAD	OS	Tertile	III,IV	0.431	0.787	.002	35	view →
ACC	DFS	Median	IV	0.069	0.421	.016	24	view →
OV	DFS	Quartile	III,IV	0.478	0.594	.007	24	view →
DLBC	DFS	Median	IV	1.000	0.412	.006	22	view →
READ	DFS	Tertile	III,IV	0.895	0.573	.012	12	view →
CHOL	OS	Tertile	II,III,IV	0.768	0.222	.023	11	view →
LUSC	OS	Median	All	0.611	0.703	.017	8	view →
THCA	DFS	Median	All	0.910	0.707	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MMADHCP2–COAD (OS)

Open the COAD breakdown →