MMADHCP1

Across TCGA pan-cancer cohorts, MMADHCP1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MMADHCP1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MMADHCP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MMADHCP1 expression acts as an unfavorable survival marker, although some lineages such as LAML and PRAD show a favorable association.

MESO, UVM, and KIRP are the cancer types where MMADHCP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	All	0.212	0.396	.001	105	view →
UVM	DFS	Tertile	II,III,IV	0.325	0.647	<.001	96	view →
KIRP	OS	Tertile	All	0.777	0.943	<.001	93	view →
KIRC	DFS	Tertile	All	0.336	0.670	.003	72	view →
THYM	OS	Tertile	III,IV	0.103	0.944	<.001	63	view →
BRCA	OS	Tertile	All	0.888	0.935	.004	44	view →
LUAD	OS	Tertile	All	0.727	0.825	.003	30	view →
READ	DFS	Quartile	IV	0.281	0.727	.005	24	view →
UCEC	DFS	Tertile	All	0.321	0.693	.007	24	view →
ACC	DFS	Quartile	All	0.295	0.700	.001	20	view →
PCPG	OS	Tertile	All	0.647	0.968	.012	9	view →
SARC	DFS	Tertile	All	0.445	0.625	.019	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

MMADHCP1–MESO (DFS)

Open the MESO breakdown →