MMADHC

Across TCGA patient cohorts, MMADHC protein abundance is significantly associated with the protein abundance of many other proteins, with 13,460 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MMADHC-associated proteins across cancer lineages are DENND4C_S989, FBXL20, and SNX11. Each is linked with MMADHC in more than 3 cancer types. Because this analysis shows association rather than direction, both MMADHC-to-partner and partner-to-MMADHC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MMADHC versus DENND4C_S989 in PDAC, with a Pearson correlation of -0.38.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MMADHC→partner) and Y-score (partner→MMADHC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	DENND4C_S989 →	-0.756	-0.316	<.001	.001	3	3
PDAC	FBXL20 →	-0.537	-0.317	<.001	<.001	3	3
OV	SNX11 →	+0.393	+0.607	.001	<.001	2	4
OV	TNRC6A_S739 →	+1.196	+0.647	<.001	<.001	3	3
OV	ZKSCAN1_S208 →	-0.704	-0.444	<.001	<.001	2	4
OV	PDS5B_T1220 →	-1.137	-0.611	.004	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,460 associations by consensus.

MMADHC vs DENND4C_S989 — PDAC

Explore this scatter interactively →