MMAB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MMAB protein abundance is significantly associated with the RNA expression of many other genes, with 6,570 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MMAB-associated genes across cancer lineages are RPL3, YARS1, and NPM1. Each is linked with MMAB in more than 9 cancer types. Because this analysis shows association rather than direction, both MMAB-to-partner and partner-to-MMAB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MMAB versus RPL3 in STOMACH, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMAB→partner) and Y-score (partner→MMAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHRPL3 →+0.814+0.671.002<.001310
OESOPHAGUSYARS1 →+1.142+0.587.001.006210
PANCREASNPM1 →+1.052+0.773.001.00139
PANCREASNHP2 →+0.993+0.766<.001<.00139
OVARYRPS2 →+0.815+0.776.007.00538
PANCREASCCT7 →+1.277+1.107<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,570 associations by consensus.

MMAB vs RPL3 — STOMACH

Per-sample scatter of MMAB vs RPL3 in STOMACH (Pearson r = 0.61).

Explore this scatter interactively →

Exploration