MMAA

Across TCGA pan-cancer cohorts, MMAA Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MMAA data layer compared with 27 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MMAA Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated MMAA expression acts as an unfavorable survival marker, although some lineages such as BLCA and UCEC show a favorable association.

BLCA, UCEC, and LUSC are the cancer types where MMAA Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	All	1.000	0.322	.013	17	view →
UCEC	DFS	Median	All	1.000	0.830	.022	8	view →
LUSC	OS	Median	All	0.081	0.818	.008	6	view →
LUAD	DFS	Median	All	0.333	0.678	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

MMAA–BLCA (DFS)

Open the BLCA breakdown →