MMAA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MMAA protein abundance is significantly associated with the RNA expression of many other genes, with 7,490 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MMAA-associated genes across cancer lineages are CYP4V2, TLR3, and NCOA4P3. Each is linked with MMAA in more than 5 cancer types. Because this analysis shows association rather than direction, both MMAA-to-partner and partner-to-MMAA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MMAA versus CYP4V2 in CCRCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMAA→partner) and Y-score (partner→MMAA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCCYP4V2 →+0.722+0.383<.001<.00136
UCECTLR3 →+1.039+0.403<.001.00136
HNSCNCOA4P3 →+0.516+0.327<.001<.00135
BRCAGINS2 →-0.849-0.319<.001<.00135
UCECMGST2 →+0.797+0.353<.001.00334
UCECHDHD3 →+0.894+0.327.001.00634
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,490 associations by consensus.

MMAA vs CYP4V2 — CCRCC

Per-sample scatter of MMAA vs CYP4V2 in CCRCC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration