MMAA

Across TCGA cell cohorts, MMAA RNA expression is significantly associated with the go_rna of many other GO terms, with 2,644 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MMAA-associated GO terms across cancer lineages are Positive regulation of chromosome separation, Cell cycle DNA replication initiation, and Nuclear cell cycle DNA replication initiation. Each is linked with MMAA in more than 7 cancer types. Because this analysis shows association rather than direction, both MMAA-to-partner and partner-to-MMAA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome separation grouped by MMAA-low versus MMAA-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMAA→partner) and Y-score (partner→MMAA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of chromosome separation →	-0.158	-0.615	<.001	.001	3	8
PANCREAS	Cell cycle DNA replication initiation →	-0.160	-0.559	.001	.002	3	8
PANCREAS	Nuclear cell cycle DNA replication initiation →	-0.160	-0.559	.001	.002	3	8
PANCREAS	Mitotic DNA replication initiation →	-0.160	-0.559	.001	.002	3	8
BREAST	Meiotic chromosome segregation →	-0.091	-0.556	.003	.002	2	8
BONE	Purkinje myocyte action potential →	+0.693	+0.547	.006	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,644 associations by consensus.

Positive regulation of chromosome separation by MMAA expression — BREAST

Explore this box plot interactively →