MLX

Across TCGA patient cohorts, MLX RNA expression is significantly associated with the protein abundance of many other proteins, with 14,260 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MLX-associated proteins across cancer lineages are PSME3, DNAJC2, and CCDC43. Each is linked with MLX in more than 4 cancer types. Because this analysis shows association rather than direction, both MLX-to-partner and partner-to-MLX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MLX versus PSME3 in LSCC, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MLX→partner) and Y-score (partner→MLX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PSME3 →	+0.402	+0.427	<.001	<.001	3	5
HNSC	DNAJC2 →	+0.430	+1.045	<.001	<.001	3	5
LUAD	CCDC43 →	+0.247	+0.336	<.001	.001	3	5
LSCC	AQR →	+0.221	+0.387	<.001	<.001	3	4
LSCC	NOC4L →	+0.224	+0.333	<.001	<.001	3	4
LSCC	NOP16 →	+0.425	+0.403	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,260 associations by consensus.

MLX vs PSME3 — LSCC

Explore this scatter interactively →