MLNR

Across TCGA pan-cancer cohorts, MLNR Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated MLNR data layer compared with 18 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher MLNR Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MLNR expression acts as an unfavorable survival marker.

SCLC, LUAD, and COAD are the cancer types where MLNR Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	All	0.082	0.708	<.001	36	view →
LUAD	OS	Median	All	0.311	0.837	<.001	33	view →
COAD	OS	Median	III,IV	0.157	0.791	.001	18	view →
STAD	OS	Median	III,IV	0.003	0.633	<.001	12	view →
SKCM	DFS	Median	All	0.087	0.757	<.001	9	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MLNR–SCLC (OS)

Open the SCLC breakdown →