MLNR

Across TCGA patient cohorts, MLNR RNA expression is significantly associated with the go_rna of many other GO terms, with 7,130 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MLNR-associated GO terms across cancer lineages are Negative regulation of telomere capping, Regulation of proteasomal ubiquitin-dependent protein catabolic process, and Response to starvation. Each is linked with MLNR in more than 21 cancer types. Because this analysis shows association rather than direction, both MLNR-to-partner and partner-to-MLNR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of telomere capping grouped by MLNR-low versus MLNR-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MLNR→partner) and Y-score (partner→MLNR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Negative regulation of telomere capping →	+0.113	+0.277	.001	<.001	3	22
ESCA	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.064	+0.310	<.001	<.001	3	22
SCLC	Response to starvation →	+0.059	+0.268	<.001	.001	3	21
UCS	Regulation of vacuole organization →	+0.078	+0.633	<.001	<.001	3	21
ESCA	Protein acetylation →	+0.056	+0.356	.005	<.001	3	21
SCLC	Vesicle targeting →	+0.067	+0.268	.001	<.001	2	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,130 associations by consensus.

Negative regulation of telomere capping by MLNR expression — SCLC

Explore this box plot interactively →