MLNR

Across TCGA patient cohorts, MLNR mutation is significantly associated with the RNA expression of many other genes, with 317 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MLNR-associated genes across cancer lineages are FAM32DP, OR51A1P, and RNA5SP72. Each is linked with MLNR in more than 2 cancer types. Because this analysis shows association rather than direction, both MLNR-to-partner and partner-to-MLNR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM32DP grouped by MLNR-low versus MLNR-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MLNR→partner) and Y-score (partner→MLNR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	FAM32DP →	+0.235	+5.035	<.001	.002	3	3
HNSC	OR51A1P →	+0.081	+5.505	<.001	.004	3	2
HNSC	RNA5SP72 →	+0.656	+5.736	<.001	.003	3	2
HNSC	RNU6-290P →	+0.549	+6.936	<.001	<.001	3	2
UCEC	RNA5SP414 →	+0.636	+2.577	<.001	.004	3	2
HNSC	ACTR3BP5 →	+0.034	+6.008	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 317 associations by consensus.

FAM32DP by MLNR expression — STAD

Explore this box plot interactively →