MLLT6

Across TCGA patient cohorts, MLLT6 protein abundance is significantly associated with the RNA expression of many other genes, with 5,882 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MLLT6-associated genes across cancer lineages are SYNRG, LASP1, and MSH2. Each is linked with MLLT6 in more than 4 cancer types. Because this analysis shows association rather than direction, both MLLT6-to-partner and partner-to-MLLT6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MLLT6 versus SYNRG in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MLLT6→partner) and Y-score (partner→MLLT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SYNRG →	+0.551	+0.507	<.001	<.001	3	5
BRCA	LASP1 →	+0.666	+0.325	<.001	.002	3	4
HNSC	MSH2 →	+0.754	+0.525	.003	.004	3	4
LSCC	TADA2A →	+0.496	+0.294	<.001	.004	3	4
BRCA	MED1 →	+1.278	+0.538	<.001	.002	3	4
HNSC	ZNHIT3 →	+0.430	+0.382	.004	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,882 associations by consensus.

MLLT6 vs SYNRG — BRCA

Explore this scatter interactively →