MLLT3

Across TCGA cell cohorts, MLLT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,515 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MLLT3-associated GO terms across cancer lineages are Hematopoietic stem cell differentiation, Acrosomal vesicle exocytosis, and Hematopoietic progenitor cell differentiation. Each is linked with MLLT3 in more than 12 cancer types. Because this analysis shows association rather than direction, both MLLT3-to-partner and partner-to-MLLT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hematopoietic stem cell differentiation grouped by MLLT3-low versus MLLT3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MLLT3→partner) and Y-score (partner→MLLT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Hematopoietic stem cell differentiation →	+0.225	+2.086	<.001	<.001	3	13
LARGE_INTESTINE	Acrosomal vesicle exocytosis →	+0.918	+1.463	<.001	.001	3	8
SKIN	Hematopoietic progenitor cell differentiation →	+0.085	+0.862	.002	.005	3	7
BONE	Acetylcholine metabolic process →	+1.192	+1.285	.004	.001	3	7
BLOOD_Leukemia	Sulfur compound biosynthetic process →	+0.053	+2.221	<.001	<.001	3	7
STOMACH	Positive regulation of dopamine receptor signaling pathway →	-0.224	-2.274	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,515 associations by consensus.

Hematopoietic stem cell differentiation by MLLT3 expression — URINARY_TRACT

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