Across TCGA patient cohorts, MLLT11 protein abundance is significantly associated with the RNA expression of many other genes, with 5,662 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MLLT11-associated genes across cancer lineages are KIF3C, MIB1, and PGRMC1. Each is linked with MLLT11 in more than 3 cancer types. Because this analysis shows association rather than direction, both MLLT11-to-partner and partner-to-MLLT11 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MLLT11→partner) and Y-score (partner→MLLT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KIF3C →	+1.583	+1.406	.004	.001	2	4
LSCC	MIB1 →	+0.610	+0.693	<.001	<.001	3	3
LSCC	PGRMC1 →	+0.828	+0.920	<.001	<.001	3	3
LSCC	LANCL1 →	+0.803	+0.733	<.001	<.001	3	3
LSCC	ZMYM2 →	+0.734	+0.757	<.001	.001	3	3
LSCC	KLHL7 →	+0.573	+0.670	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,662 associations by consensus.

Exploration

MLLT11 survival (RNA) · tumor vs normal (RNA) · all MLLT11 data types