MLLT10

Across TCGA cell cohorts, MLLT10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,185 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MLLT10-associated GO terms across cancer lineages are Subtelomeric heterochromatin formation, Lagging strand elongation, and Negative regulation of chromosome condensation. Each is linked with MLLT10 in more than 13 cancer types. Because this analysis shows association rather than direction, both MLLT10-to-partner and partner-to-MLLT10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Subtelomeric heterochromatin formation grouped by MLLT10-low versus MLLT10-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MLLT10→partner) and Y-score (partner→MLLT10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Subtelomeric heterochromatin formation →	+0.113	+0.684	.002	.001	3	14
STOMACH	Lagging strand elongation →	+0.181	+0.985	<.001	.003	3	14
LARGE_INTESTINE	Negative regulation of chromosome condensation →	+0.157	+0.867	<.001	.001	3	13
KIDNEY	Negative regulation of gene expression, epigenetic →	+0.056	+0.841	<.001	<.001	3	13
LUNG_SCLC	Mitochondrial RNA 3'-end processing →	+0.121	+0.795	<.001	.001	3	12
BREAST	Pre-miRNA processing →	+0.091	+0.740	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,185 associations by consensus.

Subtelomeric heterochromatin formation by MLLT10 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →