MLIP

Across TCGA cell cohorts, MLIP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,371 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MLIP-associated GO terms across cancer lineages are Regulation of embryonic development, Regulation of heart rate by chemical signal, and mRNA transcription by RNA polymerase II. Each is linked with MLIP in more than 5 cancer types. Because this analysis shows association rather than direction, both MLIP-to-partner and partner-to-MLIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of embryonic development grouped by MLIP-low versus MLIP-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MLIP→partner) and Y-score (partner→MLIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of embryonic development →	+0.038	+1.317	<.001	.003	3	6
BONE	Regulation of heart rate by chemical signal →	-0.413	-0.523	<.001	.001	3	6
SOFT_TISSUE	mRNA transcription by RNA polymerase II →	+0.057	+1.484	<.001	.001	3	5
LUNG_NSCLC_LUSC	Regulation of endopeptidase activity →	-0.305	-0.334	<.001	.009	3	5
SOFT_TISSUE	Regulation of NMDA receptor activity →	+1.485	+2.036	<.001	.001	3	5
SOFT_TISSUE	Protein-RNA complex assembly →	+0.057	+2.343	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,371 associations by consensus.

Regulation of embryonic development by MLIP expression — SOFT_TISSUE

Explore this box plot interactively →