MLF2

Across TCGA cell cohorts, MLF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,034 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MLF2-associated GO terms across cancer lineages are Regulation of pentose-phosphate shunt, Maintenance of presynaptic active zone structure, and Nucleosome disassembly. Each is linked with MLF2 in more than 12 cancer types. Because this analysis shows association rather than direction, both MLF2-to-partner and partner-to-MLF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of pentose-phosphate shunt grouped by MLF2-low versus MLF2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MLF2→partner) and Y-score (partner→MLF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of pentose-phosphate shunt →	+0.138	+0.487	<.001	<.001	3	13
OVARY	Maintenance of presynaptic active zone structure →	+1.162	+0.799	<.001	<.001	3	12
BLOOD_Lymphoma	Nucleosome disassembly →	+0.133	+0.916	<.001	<.001	3	12
PANCREAS	DNA replication-dependent chromatin assembly →	+0.104	+0.787	<.001	.001	3	12
BONE	Positive regulation of mitotic cytokinesis →	+0.209	+0.843	.001	<.001	3	12
SKIN	Positive regulation of pentose-phosphate shunt →	+0.151	+0.495	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,034 associations by consensus.

Regulation of pentose-phosphate shunt by MLF2 expression — SKIN

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