MLF2

Across TCGA cell cohorts, MLF2 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MLF2-associated genes across cancer lineages are FUT5, C16orf92, and ACTBL2. Each is linked with MLF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MLF2-to-partner and partner-to-MLF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FUT5 grouped by MLF2-low versus MLF2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MLF2→partner) and Y-score (partner→MLF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FUT5 →	+0.328	+3.681	<.001	.005	3	2
BLOOD_Leukemia	C16orf92 →	+0.148	+4.359	<.001	<.001	3	1
BLOOD_Leukemia	ACTBL2 →	+0.024	+3.551	<.001	.008	3	1
BLOOD_Leukemia	SLC26A5 →	+0.048	+3.453	<.001	.009	3	1
BLOOD_Leukemia	KSR2 →	+0.437	+3.798	<.001	.004	3	1
BLOOD_Leukemia	SFT2D3 →	+0.640	+3.450	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

FUT5 by MLF2 expression — BLOOD_Leukemia

Explore this box plot interactively →