MLF1

Across TCGA cell cohorts, MLF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,520 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MLF1-associated GO terms across cancer lineages are Endoplasmic reticulum to Golgi vesicle-mediated transport, Ribosomal large subunit export from nucleus, and COPII-coated vesicle budding. Each is linked with MLF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both MLF1-to-partner and partner-to-MLF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to Golgi vesicle-mediated transport grouped by MLF1-low versus MLF1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MLF1→partner) and Y-score (partner→MLF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.077	+1.136	<.001	<.001	3	10
OVARY	Ribosomal large subunit export from nucleus →	+0.121	+2.017	<.001	<.001	3	9
OVARY	COPII-coated vesicle budding →	+0.074	+1.612	.001	<.001	3	8
STOMACH	Establishment of protein localization to membrane →	+0.066	+2.844	<.001	<.001	3	8
SKIN	Regulation of protein neddylation →	+0.120	+0.963	<.001	<.001	3	8
URINARY_TRACT	Protein localization to presynapse →	-0.196	-1.776	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,520 associations by consensus.

Endoplasmic reticulum to Golgi vesicle-mediated transport by MLF1 expression — SOFT_TISSUE

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