MLEC

Across TCGA cell cohorts, MLEC RNA expression is significantly associated with the go_rna of many other GO terms, with 4,059 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MLEC-associated GO terms across cancer lineages are Rostrocaudal neural tube patterning, Peptidyl-serine phosphorylation, and Protein N-linked glycosylation. Each is linked with MLEC in more than 8 cancer types. Because this analysis shows association rather than direction, both MLEC-to-partner and partner-to-MLEC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rostrocaudal neural tube patterning grouped by MLEC-low versus MLEC-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MLEC→partner) and Y-score (partner→MLEC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Rostrocaudal neural tube patterning →	+0.108	+0.665	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Peptidyl-serine phosphorylation →	+0.075	+1.177	<.001	<.001	3	9
SKIN	Protein N-linked glycosylation →	+0.055	+0.625	<.001	.003	3	9
SKIN	Vacuole organization →	+0.052	+1.020	<.001	<.001	3	9
BLOOD_Lymphoma	Cellular response to insulin stimulus →	+0.041	+1.035	<.001	<.001	3	9
LUNG_SCLC	Establishment of protein localization to vacuole →	+0.067	+0.437	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,059 associations by consensus.

Rostrocaudal neural tube patterning by MLEC expression — LARGE_INTESTINE

Explore this box plot interactively →