MKX

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MKX protein abundance is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MKX-associated genes across cancer lineages are FKBP4P7, SNORD13P1, and PRSS3P1. Each is linked with MKX in more than 1 cancer types. Because this analysis shows association rather than direction, both MKX-to-partner and partner-to-MKX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MKX versus FKBP4P7 in BRCA, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MKX→partner) and Y-score (partner→MKX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAFKBP4P7 →+0.375+1.936<.001.00531
BRCASNORD13P1 →+1.395+1.875.004.00231
BRCAPRSS3P1 →+0.475+1.866.001.00321
BRCACCL1 →+0.485+1.800<.001.00411
BRCALIPM →+0.110+1.808<.001.00111
BRCARNU6ATAC4P →+0.955+1.808<.001.00111
Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

MKX vs FKBP4P7 — BRCA

Per-sample scatter of MKX vs FKBP4P7 in BRCA (Pearson r = 0.84).

Explore this scatter interactively →

Exploration