MKRN2

Across TCGA patient cohorts, MKRN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,794 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MKRN2-associated proteins across cancer lineages are TOP2B, WDR48, and RBSN. Each is linked with MKRN2 in more than 6 cancer types. Because this analysis shows association rather than direction, both MKRN2-to-partner and partner-to-MKRN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MKRN2 versus TOP2B in GBM, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MKRN2→partner) and Y-score (partner→MKRN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TOP2B →	+0.430	+0.279	<.001	<.001	3	7
LSCC	WDR48 →	+0.204	+0.340	.001	.005	3	6
GBM	RBSN →	+0.289	+0.317	<.001	<.001	3	6
GBM	KIAA1143 →	+0.354	+0.225	<.001	<.001	3	6
BRCA	VGLL4 →	+0.359	+0.334	<.001	.001	3	6
LSCC	DYNC1LI1 →	+0.221	+0.411	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,794 associations by consensus.

MKRN2 vs TOP2B — GBM

Explore this scatter interactively →