MKRN2

Across TCGA patient cohorts, MKRN2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,588 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MKRN2-associated genes across cancer lineages are EMC3, MTMR14, and ARPC4. Each is linked with MKRN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both MKRN2-to-partner and partner-to-MKRN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MKRN2 versus EMC3 in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MKRN2→partner) and Y-score (partner→MKRN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EMC3 →	+0.457	+0.293	.006	.007	3	4
OV	MTMR14 →	+0.514	+0.371	<.001	<.001	3	4
OV	ARPC4 →	+0.386	+0.223	.001	.006	3	4
LSCC	BRK1 →	+0.416	+0.247	<.001	<.001	3	4
UCEC	DDR2 →	+0.865	+0.235	<.001	<.001	3	4
LSCC	UBP1 →	+0.515	+0.197	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,588 associations by consensus.

MKRN2 vs EMC3 — OV

Explore this scatter interactively →