MKRN2

Across TCGA cell cohorts, MKRN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,240 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MKRN2-associated GO terms across cancer lineages are Chemokine (C-C motif) ligand 21 signaling pathway, Transcription elongation by RNA polymerase II, and P-body assembly. Each is linked with MKRN2 in more than 12 cancer types. Because this analysis shows association rather than direction, both MKRN2-to-partner and partner-to-MKRN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chemokine (C-C motif) ligand 21 signaling pathway grouped by MKRN2-low versus MKRN2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MKRN2→partner) and Y-score (partner→MKRN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Chemokine (C-C motif) ligand 21 signaling pathway →	+0.179	+1.101	<.001	.002	3	13
STOMACH	Transcription elongation by RNA polymerase II →	+0.090	+0.578	<.001	.004	3	13
OVARY	P-body assembly →	+0.092	+0.770	<.001	<.001	3	12
KIDNEY	Regulation of chromosome segregation →	+0.088	+0.981	.001	<.001	3	11
KIDNEY	Chromosome segregation →	+0.074	+0.968	<.001	<.001	3	11
KIDNEY	Protein K11-linked ubiquitination →	+0.062	+0.799	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,240 associations by consensus.

Chemokine (C-C motif) ligand 21 signaling pathway by MKRN2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →