MKRN1

Across TCGA patient cohorts, MKRN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,873 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MKRN1-associated proteins across cancer lineages are SSBP1, CDK5, and CUL1. Each is linked with MKRN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both MKRN1-to-partner and partner-to-MKRN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MKRN1 versus SSBP1 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MKRN1→partner) and Y-score (partner→MKRN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SSBP1 →	+0.578	+0.617	<.001	<.001	3	7
BRCA	CDK5 →	+0.342	+0.413	<.001	<.001	3	7
LSCC	CUL1 →	+0.314	+0.611	<.001	<.001	3	6
HNSC	RHEB →	+0.401	+0.726	<.001	<.001	3	6
LSCC	AGK →	+0.353	+0.549	<.001	<.001	3	6
LSCC	ARHGEF5 →	+0.440	+0.459	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,873 associations by consensus.

MKRN1 vs SSBP1 — LSCC

Explore this scatter interactively →