MKNK1

Across TCGA patient cohorts, MKNK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,114 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MKNK1-associated proteins across cancer lineages are FGD3, MKNK1_S221, and MRPL58. Each is linked with MKNK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MKNK1-to-partner and partner-to-MKNK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MKNK1 versus FGD3 in BRCA, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MKNK1→partner) and Y-score (partner→MKNK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FGD3 →	+0.591	+0.317	<.001	<.001	3	5
PDAC	MKNK1_S221 →	+0.486	+0.269	<.001	<.001	3	4
GBM	MRPL58 →	-0.333	-0.466	<.001	<.001	3	4
BRCA	MRPS18A →	-0.333	-0.381	<.001	.001	3	4
GBM	APOBR →	+0.486	+0.389	<.001	<.001	3	4
LUAD	CPNE2 →	+0.279	+0.336	<.001	.002	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,114 associations by consensus.

MKNK1 vs FGD3 — BRCA

Explore this scatter interactively →