MKNK1

RNA expression — cross-omics
Cross-omicsRNA → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MKNK1 RNA expression is significantly associated with the RNA expression of many other genes, with 11,205 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MKNK1-associated genes across cancer lineages are MOB3C, NRDC, and UBE4B. Each is linked with MKNK1 in more than 14 cancer types. Because this analysis shows association rather than direction, both MKNK1-to-partner and partner-to-MKNK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MKNK1 versus MOB3C in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MKNK1→partner) and Y-score (partner→MKNK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCMOB3C →+1.460+0.910<.001<.001215
BLOOD_MyelomaNRDC →+0.927+1.111<.001<.001313
PANCREASUBE4B →+0.935+0.842<.001<.001312
BLOOD_MyelomaCC2D1B →+1.056+1.091<.001<.001312
BLOOD_MyelomaEFCAB14 →+0.883+0.937<.001<.001312
UPPER_AERODIGESTIVE_TRACTDMAP1 →+1.207+1.300<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,205 associations by consensus.

MKNK1 vs MOB3C — LUNG_NSCLC_LUSC

Per-sample scatter of MKNK1 vs MOB3C in LUNG_NSCLC_LUSC (Pearson r = 0.69).

Explore this scatter interactively →

Exploration