MKLN1

Across TCGA cell cohorts, MKLN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,663 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MKLN1-associated GO terms across cancer lineages are Phosphatidylinositol metabolic process, Nucleocytoplasmic transport, and Peptidyl-serine phosphorylation. Each is linked with MKLN1 in more than 12 cancer types. Because this analysis shows association rather than direction, both MKLN1-to-partner and partner-to-MKLN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol metabolic process grouped by MKLN1-low versus MKLN1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MKLN1→partner) and Y-score (partner→MKLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.059	+1.027	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.080	+0.924	.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Peptidyl-serine phosphorylation →	+0.068	+0.802	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.079	+0.910	.002	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Peptidyl-serine modification →	+0.064	+0.720	.001	.005	3	11
BLOOD_Myeloma	Vesicle-mediated transport between endosomal compartments →	+0.072	+1.068	.007	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,663 associations by consensus.

Phosphatidylinositol metabolic process by MKLN1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →