Across TCGA patient cohorts, MIXL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,970 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MIXL1-associated proteins across cancer lineages are MZB1, CARMIL2_S1381, and IRF4. Each is linked with MIXL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both MIXL1-to-partner and partner-to-MIXL1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIXL1→partner) and Y-score (partner→MIXL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MZB1 →	+1.480	+0.645	<.001	<.001	3	8
BRCA	CARMIL2_S1381 →	+1.037	+0.413	<.001	<.001	3	7
BRCA	IRF4 →	+1.078	+0.479	<.001	<.001	3	7
OV	P2RY8_S324 →	+1.020	+0.716	<.001	<.001	3	7
LSCC	SEC11C →	+1.127	+0.570	<.001	<.001	3	6
HNSC	SEPTIN6 →	+0.427	+0.466	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,970 associations by consensus.

Exploration

MIXL1 survival (RNA) · tumor vs normal (RNA) · all MIXL1 data types