Across TCGA cell cohorts, MIXL1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible MIXL1-associated genes across cancer lineages are TBL1Y and ITGAD. Each is linked with MIXL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIXL1-to-partner and partner-to-MIXL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIXL1→partner) and Y-score (partner→MIXL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	TBL1Y →	+0.053	+4.643	<.001	.008	3	1
LARGE_INTESTINE	ITGAD →	+0.015	+4.095	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

MIXL1 survival (RNA) · tumor vs normal (RNA) · all MIXL1 data types