MITF

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MITF RNA expression is significantly associated with the protein abundance of many other proteins, with 20,705 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MITF-associated proteins across cancer lineages are RAI14, TLN1, and VCL. Each is linked with MITF in more than 8 cancer types. Because this analysis shows association rather than direction, both MITF-to-partner and partner-to-MITF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MITF→partner) and Y-score (partner→MITF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRAI14 →+0.420+0.712<.001.00139
UCECTLN1 →+0.644+1.062<.001<.00139
BRCAVCL →+0.407+0.776<.001<.00139
OVWDR1 →+0.378+0.697.002.00139
BRCAILK →+0.443+0.852<.001<.00139
COADLGALS1 →+0.558+0.597<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,705 associations by consensus.

Exploration