MITF

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MITF RNA expression is significantly associated with the go_rna of many other GO terms, with 5,627 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MITF-associated GO terms across cancer lineages are Response to salt stress, Regulation of actomyosin structure organization, and Regulation of early endosome to late endosome transport. Each is linked with MITF in more than 9 cancer types. Because this analysis shows association rather than direction, both MITF-to-partner and partner-to-MITF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MITF→partner) and Y-score (partner→MITF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTResponse to salt stress →+0.162+2.165.001<.00139
BONERegulation of actomyosin structure organization →+0.165+2.304<.001<.00139
BONERegulation of early endosome to late endosome transport →+0.118+1.626.002<.00139
LIVERRegulation of L-glutamate import across plasma membrane →+0.270+2.355<.001.00239
BONEPositive regulation of focal adhesion assembly →+0.239+2.086<.001<.00139
BONERegulation of focal adhesion assembly →+0.127+1.518<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,627 associations by consensus.

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