MITD1

Across TCGA cell cohorts, MITD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,683 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MITD1-associated GO terms across cancer lineages are Protein branched polyubiquitination, Positive regulation of maintenance of sister chromatid cohesion, and Positive regulation of maintenance of mitotic sister chromatid cohesion. Each is linked with MITD1 in more than 9 cancer types. Because this analysis shows association rather than direction, both MITD1-to-partner and partner-to-MITD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein branched polyubiquitination grouped by MITD1-low versus MITD1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MITD1→partner) and Y-score (partner→MITD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protein branched polyubiquitination →	+0.104	+0.724	<.001	<.001	3	10
OVARY	Positive regulation of maintenance of sister chromatid cohesion →	+0.089	+0.540	.006	.002	3	9
OVARY	Positive regulation of maintenance of mitotic sister chromatid cohesion →	+0.089	+0.540	.006	.002	3	9
LUNG_NSCLC_LUSC	Centrosome cycle →	+0.079	+0.694	.008	.007	2	9
LUNG_SCLC	Negative regulation of protein binding →	+0.116	+0.513	.001	.003	3	8
LUNG_NSCLC_LUSC	Microtubule organizing center organization →	+0.093	+0.918	.006	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,683 associations by consensus.

Protein branched polyubiquitination by MITD1 expression — BREAST

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