MIS18BP1

Across TCGA patient cohorts, MIS18BP1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,617 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MIS18BP1-associated genes across cancer lineages are VRK1, EZH2, and FOXM1. Each is linked with MIS18BP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MIS18BP1-to-partner and partner-to-MIS18BP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIS18BP1 versus VRK1 in LSCC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIS18BP1→partner) and Y-score (partner→MIS18BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VRK1 →	+0.775	+0.495	<.001	<.001	3	4
LSCC	EZH2 →	+1.108	+0.717	<.001	<.001	3	4
BRCA	FOXM1 →	+1.126	+0.420	.002	.005	3	4
UCEC	ECT2 →	+1.099	+0.556	<.001	<.001	3	4
BRCA	STMN1 →	+1.002	+0.605	<.001	<.001	3	4
UCEC	KIF18A →	+0.838	+0.451	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,617 associations by consensus.

MIS18BP1 vs VRK1 — LSCC

Explore this scatter interactively →