MIRLET7F1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIRLET7F1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIRLET7F1-associated genes across cancer lineages are MIR4476, MIR412, and TSPY8. Each is linked with MIRLET7F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIRLET7F1-to-partner and partner-to-MIRLET7F1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIRLET7F1→partner) and Y-score (partner→MIRLET7F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR4476 →+0.736+8.066<.001.00731
UCECMIR412 →+0.621+8.066<.001.00731
UCECTSPY8 →+0.039+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

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