Across TCGA patient cohorts, MIRLET7A2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIRLET7A2-associated genes across cancer lineages are RNU6-73P, MTND2P22, and MAGEB6B. Each is linked with MIRLET7A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIRLET7A2-to-partner and partner-to-MIRLET7A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIRLET7A2→partner) and Y-score (partner→MIRLET7A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-73P →	+0.714	+6.226	<.001	.001	3	1
UCEC	MTND2P22 →	+0.101	+5.420	.005	.005	3	1
UCEC	MAGEB6B →	+0.206	+5.081	<.001	.008	3	1
UCEC	RPL23AP68 →	+0.316	+5.133	<.001	.008	3	1
UCEC	SNX18P23 →	+0.148	+5.694	<.001	.003	3	1
UCEC	LINC01216 →	+0.177	+5.852	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

MIRLET7A2 survival (RNA) · tumor vs normal (RNA) · all MIRLET7A2 data types