MIRLET7A1HG

Across TCGA pan-cancer cohorts, MIRLET7A1HG RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated MIRLET7A1HG data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher MIRLET7A1HG RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIRLET7A1HG expression acts as an unfavorable survival marker, although some lineages such as PAAD and UCS show a favorable association.

CESC, PAAD, and UVM are the cancer types where MIRLET7A1HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Quartile	II,III,IV	0.688	0.917	.003	56	view →
PAAD	OS	Median	All	0.516	0.278	<.001	54	view →
UVM	DFS	Median	III,IV	0.261	0.651	.004	50	view →
UCS	OS	Tertile	III,IV	0.572	0.216	.018	42	view →
KIRC	OS	Median	All	0.919	0.828	<.001	41	view →
MESO	DFS	Tertile	IV	0.076	0.504	.001	36	view →
UCEC	OS	Median	III,IV	0.760	0.879	.005	34	view →
COAD	DFS	Median	II,III,IV	0.651	0.406	.008	22	view →
LUAD	DFS	Tertile	IV	0.573	0.872	.011	21	view →
SARC	OS	Quartile	All	0.877	0.670	.009	20	view →
LGG	DFS	Tertile	All	0.753	0.875	<.001	18	view →
LIHC	DFS	Median	All	0.480	0.609	.010	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

MIRLET7A1HG–CESC (DFS)

Open the CESC breakdown →