Across TCGA patient cohorts, MIRLET7A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,949 significant associations in total. THCA shows the largest number of these associations.

The most reproducible MIRLET7A1-associated GO terms across cancer lineages are Negative regulation of interleukin-6-mediated signaling pathway, Regulation of interleukin-6-mediated signaling pathway, and Regulation of canonical Wnt signaling pathway. Each is linked with MIRLET7A1 in more than 27 cancer types. Because this analysis shows association rather than direction, both MIRLET7A1-to-partner and partner-to-MIRLET7A1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIRLET7A1→partner) and Y-score (partner→MIRLET7A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Negative regulation of interleukin-6-mediated signaling pathway →	-0.236	-0.415	<.001	<.001	3	28
TGCT	Regulation of interleukin-6-mediated signaling pathway →	-0.103	-0.467	<.001	<.001	2	25
ESCA	Regulation of canonical Wnt signaling pathway →	+0.034	+0.431	.003	.004	2	12
TGCT	Interleukin-6-mediated signaling pathway →	-0.039	-0.271	<.001	<.001	3	11
ESCA	Glycerolipid biosynthetic process →	+0.027	+0.277	.003	.005	1	12
ESCA	Positive regulation of translation →	+0.048	+0.454	.001	.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,949 associations by consensus.

Exploration

MIRLET7A1 survival (RNA) · tumor vs normal (RNA) · all MIRLET7A1 data types