Across TCGA patient cohorts, MIR889 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR889-associated genes across cancer lineages are RN7SKP45, RNU6-618P, and RNU6-340P. Each is linked with MIR889 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR889-to-partner and partner-to-MIR889 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR889→partner) and Y-score (partner→MIR889) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP45 →	+0.355	+5.335	<.001	.003	3	1
UCEC	RNU6-618P →	+0.616	+4.969	<.001	.002	3	1
UCEC	RNU6-340P →	+0.447	+5.027	<.001	.004	3	1
UCEC	RNA5SP205 →	+0.817	+4.852	<.001	.006	3	1
UCEC	RNA5SP334 →	+0.417	+4.852	<.001	.006	3	1
UCEC	RNU6-737P →	+0.461	+5.722	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

MIR889 survival (RNA) · tumor vs normal (RNA) · all MIR889 data types