MIR8071-1

Across TCGA pan-cancer cohorts, MIR8071-1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of MIR8071-1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MIR8071-1 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR8071-1 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

THCA, BRCA, and COAD are the cancer types where MIR8071-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR8071-1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−1.724	<.001	7	view →
BRCA	All	III,IV	+1.891	<.001	6	view →
COAD	Female	III,IV	−2.372	<.001	5	view →
LIHC	Female	All	−1.104	<.001	5	view →
LUAD	All	IV	−1.895	.026	2	view →
PAAD	Male	All	−1.050	.004	2	view →
LUAD	All	All	+0.900	.005	2	view →
KICH	All	All	−0.710	.019	2	view →
CHOL	Male	All	−1.381	.007	1	view →
HNSC	All	III,IV	+0.613	.048	1	view →
KIRC	Female	All	+0.553	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

MIR8071-1–THCA

Open the THCA breakdown →