Across TCGA pan-cancer cohorts, MIR8067 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR8067’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR8067 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR8067 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.
KIRC and LUAD are the cancer types where MIR8067 tumor–normal differential expression is most reproducible.