MIR7854

Across TCGA pan-cancer cohorts, MIR7854 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR7854’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MIR7854 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR7854 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

HNSC, LUSC, and KICH are the cancer types where MIR7854 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR7854 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	+0.600	<.001	6	view →
LUSC	Male	All	+0.488	<.001	4	view →
KICH	All	All	−0.399	.013	4	view →
KIRP	Male	All	−0.342	.028	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR7854–HNSC

Open the HNSC breakdown →