Across TCGA pan-cancer cohorts, MIR708 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MIR708’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MIR708 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR708 is over-expressed in tumor, although a few such as UCEC and THCA show the opposite, repressed pattern.

HNSC, UCEC, and THCA are the cancer types where MIR708 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR708 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.587	<.001	8	view →
UCEC	All	All	−0.713	.004	6	view →
THCA	Female	All	−0.798	<.001	4	view →
BLCA	All	IV	−0.667	.037	2	view →
BRCA	Female	All	−0.160	.016	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: MIR708 RNA expression & survival · all MIR708 data types