Across TCGA pan-cancer cohorts, MIR7-2 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MIR7-2 data layer compared with 3 for mutation status.
The strongest signal is observed in breast invasive carcinoma (BRCA), where higher MIR7-2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR7-2 expression acts as an unfavorable survival marker, although some lineages such as LGG and HNSC show a favorable association.
BRCA, ACC, and THCA are the cancer types where MIR7-2 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.