MIR7-2

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR7-2 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MIR7-2 data layer compared with 9 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher MIR7-2 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR7-2 expression acts as an unfavorable survival marker.

LUSC, SKCM, and PRAD are the cancer types where MIR7-2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCDFSMedianAll0.2310.758.01718view →
SKCMDFSMedianAll0.0880.737<.00118view →
PRADDFSMedianAll0.0850.774<.0016view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration