MIR6870

Across TCGA pan-cancer cohorts, MIR6870 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated MIR6870 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MIR6870 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR6870 expression acts as an unfavorable survival marker, although some lineages such as LAML and COAD show a favorable association.

UVM, PAAD, and CHOL are the cancer types where MIR6870 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	III,IV	0.136	0.874	<.001	117	view →
PAAD	OS	Quartile	II,III,IV	0.383	0.614	.001	45	view →
CHOL	DFS	Tertile	III,IV	0.031	0.505	.003	45	view →
READ	OS	Tertile	III,IV	0.480	0.911	<.001	42	view →
LGG	OS	Tertile	All	0.802	0.910	.001	33	view →
STAD	DFS	Median	All	0.594	0.780	.006	29	view →
SKCM	DFS	Tertile	IV	0.101	0.517	.015	27	view →
LAML	DFS	Median	All	0.671	0.475	.004	26	view →
BRCA	OS	Tertile	All	0.896	0.931	.026	12	view →
PRAD	DFS	Tertile	All	0.896	0.940	.036	12	view →
COAD	DFS	Tertile	All	0.910	0.519	.028	9	view →
LUSC	DFS	Median	All	0.688	0.797	.010	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

MIR6870–UVM (OS)

Open the UVM breakdown →