MIR6859-4

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR6859-4 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MIR6859-4 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher MIR6859-4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MIR6859-4 expression acts as an unfavorable survival marker.

THYM and LIHC are the cancer types where MIR6859-4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THYMOSMedianIII,IV0.1030.944<.00142view →
LIHCDFSMedianAll0.0430.527<.0013view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

MIR6859-4–THYM (OS)

Kaplan–Meier survival curve for MIR6859-4 mutant vs wild-type samples in THYM.

Open the THYM breakdown →

Exploration